It would be an understatement to say there is a huge amount riding on Saturday's Six Nations finale at the Principality Stadium.
A bonus-point victory for England will give them a chance of getting crowned Six Nations champions, whereas Wales are hell bent on avoiding the ignominy of back-to-back whitewashes. Matt Sherratt's approach is the polar opposite to Steve Borthwick's.
The Wales boss has gone for continuity, opting to tinker with his side, while Borthwick has shaken up his England squad. Aaron Wainwright's elevation to the starting XV in place of Tommy Reffell arguably gives the Wales backrower a better balance.
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The backrow of Wainwright on the blindside, Jac Morgan at number seven and the indomitable Taulupe Faletau at No 8 was the loose forward trio which went well at the Rugby World Cup.
Reffell has got through a mountain of work over the past couple of weekends, putting in 17 and 15 tackles against Ireland and Scotland, respectively.
The dual openside option went well against Ireland but it wasn't very effective up in Murrayfield as Wales failed to slow down the speed of Scotland's ruck ball. Wales do lack carriers capable of making significant post-contact metres and this is an area where Wainwright is superior to the Leicester Tigers openside.
Sherratt will want both Wainwright and Faletau getting over the gainline while also making headway in the wide channels.
There was a big clamour to promote Teddy Williams and Dewi Lake into the starting XV, but Sherratt has resisted this urge.
Cardiff lock Williams is an athletic second row who was very impressive as a replacement in Murrayfield where he claimed his first international try. On the flipside Will Rowlands has not been at his best this season, but the Racing 92 lock is almost a stone heavier than Williams.
Lake is another explosive carrier but Elliot Dee's darts are the most accurate at the lineout which has probably won him the nod. But Ospreys hooker Lake is the more physical player and the better carrier.
England will try to bully Wales' pack and have gone with a 6-2 split on the bench with no second-row or centre cover. Sherratt will hope Lake can wreak havoc with his explosive carrying and he is one of the only Wales players who can win collisions in the tight while also making post-contact metres.
Slowing down the speed of England's ruck ball will be crucial. Wales are pretty good at defending against strong packs who take a route one approach but are not so good when the game quickens and the likes of Ben Earle and Tom Curry are running into space in the wider channels because it becomes more difficult to commit two defenders to the tackle.
England also have a dangerous backline - if Borthwick gives them licence to play - with the likes of Marcus Smith capable of ripping defences to shreds.
The biggest surprise in the backline is Sherratt's decision to start Joe Roberts on the wing.
Roberts is considered an out-and-out 13 but did well as a replacement on the wing in Scotland as a result of Tom Rogers getting forced from the field of play with a fractured thumb. Sherratt could have thrown Gloucester's Josh Hathaway straight into the starting XV as a like-for-like replacement for Rogers but the Gloucester flyer's defence is suspect.
Pushing Max Llewellyn out to the wing, where he has played for Gloucester, would have been another option but Sherratt wouldn't have wanted to mess up a centre partnership which is beginning to purr. There would also have been a debate over whether Jarrod Evans should have started at outside-half over Gareth Anscombe.
But Evans is arguably better suited as a replacement when the game is slightly more unstructured and will have a big role to play in the final quarter of this Test match. Wales lost the kicking game hands down at Murrayfield so there will be a big onus on both Anscombe and Ben Thomas to put Sherratt's men into the right areas.
But Wales' chances of ending a barren run of 16 straight defeats will depend on how they contain England's power and physicality, along with how clinical they can be. Wales have shown signs over the previous two games they are getting closer to that elusive victory and Sherratt will hope they have enough to get over the line this time around.